"Artificial Intelligence + Brain-Computer Interface + Neuromodulation" Triple Empowerment: HSAP Fortifies the Frontline for Early Screening, Diagnosis, and Treatment of Alzheimer's Disease
Addressing the diagnostic and therapeutic challenges of Alzheimer's disease (AD)-characterized by its insidious onset and irreversible progression- HSAP Medical Systems Co., Ltd. has independently developed the ADDS Cognitive Impairment Screening System and the ADTS Memory Impairment Training System. These systems deeply integrate three core technologies-artificial intelligence, brain-computer interfaces, and neuromodulation-to establish a closed-loop "screening-intervention-rehabilitation" process. They precisely align with the integrated diagnostic requirements outlined in the 2025 edition of the Chinese Guidelines for the Diagnosis and Treatment of Alzheimer's Disease and Dementia, providing an efficient, replicable, China-originated solution for early screening and treatment. Currently deployed across multiple provinces and municipalities nationwide, these systems represent a highly effective, replicable, and domestically developed solution.
The current situation of Alzheimer's disease (AD) prevention and control in China is severe. Data indicate that the rate of early-stage AD diagnosis is only 28.6%, while the rate for mild cognitive impairment is less than 3%. By the time of diagnosis, 95% of patients have already reached the middle or late stages of the disease. This not only misses the optimal window for intervention but also imposes a heavy caregiving burden on families and society. The National Action Plan for Dementia in Later Life (2024–2030), jointly issued by 15 government departments including the National Health Commission, explicitly calls for comprehensive advancement of early AD screening and targeted interventions to fortify defenses for cognitive health in the elderly. Technological innovation stands as the key to unlocking this challenge.

The HSAP dual-system leverages technological synergy to bridge gaps in Alzheimer's disease diagnosis and treatment, providing a precise tool for early detection. The ADDS cognitive impairment screening system employs non-invasive brain-computer interface technology. Using high-precision electrodes to collect real-time neural signals, it integrates proprietary AI deep learning algorithms to quantitatively assess six cognitive dimensions-including memory, attention, and executive function. The process is entirely non-invasive, pain-free, and user-friendly, delivering precise reports within 15 minutes with over 90% screening accuracy. This system meets the precise diagnostic needs of top-tier hospitals like Tongji Hospital while also being adaptable for large-scale population screening in community and primary healthcare settings. It effortlessly enables risk stratification for high-risk individuals, securing the golden window for early intervention.

In the "early intervention" phase, the ADTS Memory Impairment Training System leverages neuromodulation technology as its core, combined with AI-driven personalized adaptation capabilities, to create targeted rehabilitation protocols. Patients control the progression of rehabilitation games through mental focus, activating cortical neurons to enhance brain KC values and approximate entropy. This strengthens cognitive focus and complexity, delaying cognitive decline at its root. Clinical data confirms that patients with mild to moderate cognitive impairment who undergo continuous training for over three months achieve an average MMSE score improvement of 4-6 points, with significant enhancements in activities of daily living. This aligns perfectly with the guideline's cognitive training protocol of "3-5 sessions per week for over three months," addressing the shortcomings of traditional rehabilitation-which relies on experience and lacks targeting.
More notably, the dual-system achieves a closed-loop neuromodulation cycle of "assessment-intervention-monitoring-optimization," truly integrating the entire chain of AD early screening, diagnosis, and treatment: Primary care facilities use ADDS for initial screening. Positive cases are referred via a green channel to higher-level hospitals for precise diagnosis. After confirmation, patients undergo personalized rehabilitation training through ADTS. AI algorithms continuously monitor training effectiveness, dynamically optimizing protocols to achieve full-cycle management characterized by evidence-based screening, targeted intervention, and tracked rehabilitation.
Currently, this technological solution has been widely implemented across various medical settings nationwide: Top-tier tertiary hospitals such as Tongji Hospital affiliated with Tongji Medical College of Huazhong University of Science and Technology utilize it to enhance diagnostic accuracy for complex cases; Mental Health Centers in Shanghai's Jing'an and Changning districts employ it for community-based early screening, improving treatment adherence among individuals with declining cognitive function; Primary care institutions like Qian'an People's Hospital and LiPu People's Hospital in Guangxi leverage technology decentralization to address the lack of precise screening tools, extending early AD diagnosis to county-level regions. Stroke centers such as the Fourth Affiliated Hospital of Guangzhou Medical University utilize it for post-stroke cognitive impairment rehabilitation, completing the full spectrum of neurodiagnostic and therapeutic services.
"The HSAP dual-system has transformed traditional AD cognitive diagnosis and treatment models. AI's iterative capabilities make personalized therapy more reliable, while the integration of brain-computer interfaces and neuromodulation enables more precise interventions-these are the core enablers for implementing early screening, diagnosis, and treatment," "A leading domestic neurology expert stated that this technology not only lowers the technical barriers for AD prevention and treatment but also provides core equipment for building a national cognitive health prevention and control network for the elderly, leveraging its non-invasive, efficient, and widely adaptable advantages."




